Intimate 10 mg Tablet

Overview

Intimate 10 mg Tablet contains Tadalafil 10 mg, a selective phosphodiesterase type 5 (PDE5) inhibitor used in the treatment of Erectile Dysfunction (ED), Benign Prostatic Hyperplasia (BPH), or a combination of both conditions. Tadalafil inhibits PDE5, increasing cyclic guanosine monophosphate (cGMP) in smooth muscle cells, which promotes smooth muscle relaxation and enhanced blood flow into the corpus cavernosum to produce penile erection. PDE5 inhibition in the prostate and bladder wall relaxes smooth muscle, improves urinary blood flow, and widens the bladder neck opening for better voiding. The 10 mg dose is the recommended starting dose for most patients with ED and may be adjusted up to 20 mg or down to 5 mg based on individual response and tolerability.

Dosage and Administration

Erectile Dysfunction: The recommended starting dose is 10 mg before anticipated sexual activity. The dose may be increased to 20 mg or decreased to 5 mg based on individual efficacy and tolerability. The maximum dosing frequency is once per day. Tadalafil remains effective for up to 36 hours.

Benign Prostatic Hyperplasia: The recommended dose is 5 mg taken at the same time every day (the 5 mg tablet is typically prescribed for this indication).

Combined ED and BPH: The recommended dose is 5 mg taken at the same time every day.

Interaction

Intimate may interact with nitrates (e.g., Isosorbide, Nitroglycerin), Alpha adrenergic blockers, antihypertensives, alcohol, antacids (magnesium hydroxide/aluminium hydroxide), Ketoconazole, Ritonavir, Erythromycin, Itraconazole, grapefruit juice, other HIV protease inhibitors, Rifampin, Carbamazepine, Phenytoin, and Phenobarbital. Concurrent use with nitrates may cause dangerous hypotension.

Contraindications

Intimate is contraindicated in patients using nitrates (e.g., Nitroglycerin, Isosorbide) due to the risk of potentiated hypotensive effects, and in patients with hypersensitivity to Tadalafil or any component of the formulation.

Side Effects

Common side effects include headache, dyspepsia, back pain, myalgia, nasopharyngitis, and nasal congestion. Rare but serious effects may include change in colour vision, sudden vision loss, hearing loss, Stevens-Johnson Syndrome, exfoliative dermatitis, angina, stroke, myocardial infarction, severe hypotension, and tachycardia.

Pregnancy and Lactation

Tadalafil is assigned to pregnancy category B by the USFDA. It is only recommended for use during pregnancy when the benefit outweighs potential risk. There are no data on excretion of Tadalafil in human breast milk; caution is advised when administering to nursing women.

Precautions and Warnings

Use with caution in patients with angina, renal impairment, or hepatic impairment. Concomitant use with nitrates, alpha blockers, alcohol, or CYP3A4 inhibitors (e.g., Ritonavir, Ketoconazole, Itraconazole) requires careful monitoring. Do not combine with other PDE5 inhibitors. Seek medical advice before use if any cardiovascular conditions are present.

Storage Conditions

Keep in a dry place, away from light and heat. Keep out of the reach of children.

Frequently Asked Questions

Q: What is Intimate 10 mg used for?
Intimate 10 mg (Tadalafil) is the standard starting dose for treating Erectile Dysfunction (ED). It works by increasing blood flow to the penis through PDE5 inhibition, enabling an erection in response to sexual stimulation. It may also be used as part of treatment for Benign Prostatic Hyperplasia by relaxing smooth muscle in the prostate and bladder to improve urinary symptoms.

Q: Can the dose of Intimate 10 mg be adjusted?
Yes. If the 10 mg dose is insufficient, the physician may increase it to 20 mg. If the 10 mg dose causes troublesome side effects, it can be reduced to 5 mg. The maximum recommended frequency is once per day. Always follow your physician's prescription and do not adjust the dose without medical guidance.