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Sefril 100 ml susp

Sefril 100 ml susp in Bangladesh,Sefril 100 ml susp price , usage of Sefril 100 ml susp
Sefril 100 ml susp
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Sefril 100 ml susp

Composition

Each ml contains Gentamicin Sulfate USP equivalent to Gentamicin 100 mg.

Pharmacology

Gentamicin is bactericidal and is a broad spectrum antibiotic (except against streptococci and anaerobic bacteria). Gentamicin inhibits bacterial protein synthesis by binding to 30s ribosomal subunit.

Indications

Pneumonia, bronchitis, enteritis, hemorrhagic septicemia, mastitis, endometritis, urinary tract infection, brucellosis, bacterial diarrhea, salmonellosis, septicemia and mycoplasmosis. To prevent secondary bacterial infection in case of viral diseases (such as PPR, FMD etc).

Dosage & Administration

Route of administration: IM/IV/SC For intramuscular/intravenous injection only

Cattle/Buffalo/Horse: 1.0 ml/25 kg body weight.

Goat/Sheep/Dog/Cat/Other small animals: 0.4-1.0 ml/10 kg body weight.

Administer by deep intramuscular or slow intravenous injection twice on the first day of treatment at 12 hours interval and repeat from second day once daily for 3-5 days.

For intramuscular/subcutaneous injection only Poultry: 0.05-0.1 ml/ kg body weight.

Administer by intramuscular or subcutaneous injection twice on the first day of treatment at 12 hours interval and repeat from 2nd day once daily for 3-5 days.

Or, as directed by the Registered Veterinary Physician.

Withdrawal period

Meat: 7 days & Milk: 2 days.

Contraindication

It is contraindicated to animals hypersensitive to Gentamicin. It is also contraindicated in pregnancy.

Side Effects

Common side effect: Nausea, vomiting, stomach upset, loss of appetite, and injection site reactions (pain, irritation, and redness) may be seen.

Rare side effect: Hypocalcemia, neuromuscular paralysis, nephrotoxicity and ototoxicity have been reported with high and prolonged medication.

Warning and Precaution

Antibiogram is recommended before administration. In case of urinary tract infection alkaline feed is recommended.

Use in pregnancy & lactation

Should not be used in pregnant or lactating animals. However, risk & necessity should be considered during administration of medicine in pregnant & lactating animals.

Drug interactions

With medicine: Potential drug interaction may occur with other aminoglycosides and bacteriostatic antibiotics.

With feed & others: Not known.

Overdose

Early signs of toxicity include loss of hearing and balance or vomiting. Moreover, increase or decrease in water intake, loss of appetite, depression, coma and death may be reported.

Storage

Store below 30° C temperature & dry place, protected from light. Keep all medicines out of reach of children.

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