- Stock: 2-3 Days
- Brand: Drug International Limited
- Product ID: Azithromycin
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Azimex Susp. 50ml — Azithromycin 200mg/5ml Oral Suspension for Larger Paediatric Courses
| Attribute | Details |
|---|---|
| Brand Name | Azimex |
| Generic Name | Azithromycin |
| Strength | 200 mg / 5 mL |
| Dosage Form | Oral Suspension (after reconstitution) |
| Pack Size | 50 mL bottle |
| Total Azithromycin | 2000 mg per bottle |
| Drug Class | Macrolide Antibiotic (Azalide) |
| Manufacturer | Drug International Limited, Bangladesh |
| Route of Administration | Oral |
About Azimex 50ml Suspension
Azimex Susp. 50ml is an oral suspension of azithromycin 200 mg per 5 mL manufactured by Drug International Limited, Bangladesh. The 50 mL bottle provides 2000 mg total azithromycin — the largest single-bottle volume in the Azimex suspension range. This pack size is designed for heavier paediatric patients (25–40+ kg) who require higher per-dose volumes, or for standard-weight children who need extended 5-day courses where the 30 mL bottle falls short. Azimex 50mL also serves as the practical option for adult patients who are unable to swallow tablets and require an oral liquid formulation (e.g., elderly patients, patients with dysphagia, or patients with nasogastric tubes). Drug International Limited is a WHO-certified Bangladeshi manufacturer supplying multiple antibiotic formulations to the local and export markets.
Weight-Based Dosing Guide for the 50ml Bottle
Using Azimex 200mg/5mL suspension at the standard paediatric dose of 10 mg/kg/day:
| Weight | Daily Dose | Daily Volume | 3-day total | 5-day total |
|---|---|---|---|---|
| 25 kg | 250 mg | 6.25 mL | 18.75 mL ✓ | 31.25 mL ✓ |
| 30 kg | 300 mg | 7.5 mL | 22.5 mL ✓ | 37.5 mL ✓ |
| 35 kg | 350 mg | 8.75 mL | 26.25 mL ✓ | 43.75 mL ✓ |
| 40 kg | 400 mg | 10 mL | 30 mL ✓ | 50 mL ✓ (exact) |
| 45 kg | 450 mg | 11.25 mL | 33.75 mL ✓ | 56.25 mL ✗ need 2 bottles |
The 50mL bottle is sufficient for a 5-day course up to 40 kg. For adult dosing (500mg/day = 12.5mL/day), a 5-day course requires 62.5mL — two 50mL bottles. For a 3-day adult course: 3 × 12.5mL = 37.5mL — one 50mL bottle is adequate.
Azimex 50ml for Typhoid Fever in Older Children and Adolescents
Typhoid fever (enteric fever) caused by Salmonella typhi remains a significant public health concern in Bangladesh. Azithromycin is recommended as a first-line oral treatment for uncomplicated typhoid fever, particularly in areas with high rates of fluoroquinolone-resistant and multidrug-resistant (MDR) Salmonella typhi — which includes most of South Asia. For typhoid treatment: the standard paediatric dose is 20 mg/kg/day (max 1g/day) for 7 days. Using Azimex 200mg/5mL at 20mg/kg/day: a 30kg child needs 300mg = 7.5mL/day × 7 days = 52.5mL (one 50mL bottle is insufficient — two may be needed or use tablets for older children); a 25kg child: 250mg = 6.25mL/day × 7 days = 43.75mL — fits within the 50mL bottle. For older children ≥25 kg who can swallow tablets, Azimex tablets (250mg or 500mg) are more practical for 7-day typhoid courses. Azimex 50mL suspension at 20mg/kg/day is best suited for the 20–25 kg range for typhoid courses.
Azithromycin Liquid for Patients with Swallowing Difficulties
A significant but underappreciated use of azithromycin oral suspension in Bangladesh is for adult patients with dysphagia (difficulty swallowing). Patients who cannot safely swallow tablets include: elderly patients with neurological conditions (stroke, Parkinson's disease, dementia) causing impaired swallowing; post-operative patients with oesophageal or throat surgery; patients with oesophageal stricture, achalasia, or oesophageal motility disorders; patients using nasogastric (NG) or percutaneous endoscopic gastrostomy (PEG) tubes; and patients with significant nausea who cannot retain solid dosage forms. For adult dosing via suspension: 500mg/day = 12.5mL once daily (from Azimex 200mg/5mL); 250mg/day = 6.25mL once daily. The Azimex 50mL bottle provides enough for a 3-day adult course (37.5mL needed) or a 4-day course (50mL exact). For community-acquired pneumonia in dysphagia patients: 500mg/day × 3 days = 37.5mL total from the 50mL bottle, with 12.5mL volume margin.
Frequently Asked Questions (FAQ)
Q1: How should the Azimex 50ml suspension be reconstituted and stored?
Reconstitution: Add the required volume of cooled boiled water (amount specified on the bottle label) in two portions — add approximately half the water, shake vigorously to loosen the powder from the bottom and sides, then add the remaining water and shake again until the powder is fully dissolved and the suspension is uniform. Do not add all water at once as this makes thorough mixing more difficult. Storage after reconstitution: Store at room temperature (not in the refrigerator unless the label specifies). Keep the bottle tightly capped. Use within 10 days of reconstitution. Shake well before each use — the suspension settles and must be resuspended before measuring each dose. Label the bottle with the reconstitution date to track the 10-day use window.
Q2: Can Azimex 50ml suspension be given through a feeding tube?
Yes, azithromycin suspension is suitable for administration via nasogastric (NG) or PEG feeding tubes. Key steps: measure the prescribed volume of Azimex suspension using a calibrated oral syringe; flush the tube with 10mL of cooled boiled water before administering the drug; administer the suspension slowly through the tube; flush again with 10mL water after the dose to ensure complete delivery and to prevent tube blockage. Do not mix azithromycin suspension with tube feed formula directly in the syringe — administer them separately with a water flush between. Azithromycin oral suspension is well absorbed via NG/PEG tube, with bioavailability comparable to oral tablet administration when the tube tip is in the stomach or jejunum.
Q3: My child weighs 35 kg — will one 50ml bottle be enough for a full course?
For a standard 3-day respiratory infection course: 350mg/day × 3 days = 1050mg = 26.25mL — one 50mL bottle is more than sufficient with 23.75mL to spare. For a 5-day course: 350mg × 5 days = 1750mg = 43.75mL — one 50mL bottle is sufficient with 6.25mL remaining. For typhoid fever (20mg/kg/day × 7 days): 700mg/day × 7 days = 4900mg = 122.5mL — three 50mL bottles would be needed; switching to Azimex tablets is more practical at 35kg. For most standard antibiotic indications in a 35kg child, one 50mL bottle covers the complete course.
Q4: Is azithromycin suspension the same strength as azithromycin tablets?
Yes — Azimex suspension (200mg/5mL) and Azimex tablets (250mg or 500mg) contain the same active ingredient (azithromycin) with equivalent bioavailability. The 200mg/5mL suspension delivers: 5mL = 200mg; 6.25mL = 250mg (equivalent to one 250mg tablet); 12.5mL = 500mg (equivalent to one 500mg tablet). So if a prescription says "azithromycin 250mg once daily for 5 days" and you use Azimex 50mL suspension, you would take 6.25mL once daily for 5 days. The clinical effect is the same regardless of whether tablets or suspension is used, provided the dose (in mg) is equivalent. Always measure suspension doses with a calibrated oral syringe rather than a household teaspoon.
Medical Disclaimer: Azimex 50ml Suspension dosing must be calculated by a physician or pharmacist based on current body weight. Do not adjust doses without medical guidance. Complete the prescribed course fully. After reconstitution, discard unused suspension after 10 days.
